Technology
Aureka Biotechnologies is developing a best-in-class therapeutic discovery platform.

By integrating high-throughput, single-cell-based functional screening and AI-based drug design and development, each experiment can interrogate millions of therapeutic candidates and generate large-scale, multi-metric data associated with each candidate with respect to function, binding, and developability. The efficient iteration among design, build, test and learn enables us to develop a pipeline that can exponentially accelerate therapeutic design.

By unlocking the design principles of immunity, we can transform the immunotherapeutic design from an empirical and trial-and-error approach to truly rational engineering practice.

Single-cell digital biology

High-throughput
functional screening
Big data
AI
De novo
drug design

Decode nature’s design principle

01 Functional screening using high-resolution, single-cell imaging.

Our proprietary high-resolution and high-throughput single-cell functional screening platform enables us to significantly increase discovery efficiency while generating indexable, content rich data for each cell. This results in abundant, high-quality training sets for our deep reinforcement learning techniques.

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Transform the traditional quantitative discovery process into a qualitative one
02 Protein geometric language model and deep reinforcement learning.

We employed geometric-aware protein language model and reinforcement learning to drive the design, build, test and learn cycle. As the explosion of structural and functional in-house data increases, our engines become more accurate and rational.

Cell factory
03 Bioengineered technologies to mine, synthesize and characterize therapeutic candidates at scale.

We are developing technologies that can mine the functional sequence space using libraries with unprecedented high diversity to enable discovery and data generation. Our pipeline also integrates high-throughput protein synthesis and characterization to evaluate the AI-designed therapeutic candidates at scale.

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